Search results for "Gastrointestinal tissue"

showing 1 items of 1 documents

2016

Objectives Human leukocyte antigen (HLA)-B27 (B27) is the strongest genetic factor associated with development of Ankylosing Spondylitis and other spondyloarthropathies (SpA), yet the role it plays in disease pathogenesis remains unclear. We investigated the expression of potentially pathogenic non-conventional heavy chain forms (NC) of B27 in synovial and intestinal tissues obtained from SpA patients. We also determined the presence of NC-B27 in joints, lymphoid and gastrointestinal tissue from B27 transgenic (TG1) rats with M.tuberculosis-induced SpA.

musculoskeletal diseases030203 arthritis & rheumatologyHLA-B27Ankylosing spondylitisHeavy chainPathologymedicine.medical_specialtybusiness.industryTransgeneImmunologyHuman leukocyte antigenDisease pathogenesismedicine.disease3. Good health03 medical and health sciences0302 clinical medicineImmunologymedicineImmunology and AllergyGastrointestinal tissueskin and connective tissue diseasesbusiness030215 immunologyJournal of Autoimmunity

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PEPhysical Sciences and Engineering
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LSLife Sciences
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  - LS4_1Organ and tissue physiology and pathophysiology
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  - LS4_5Non-hormonal mechanisms of inter-organ and tissue communication
  - LS4_6Microbiome and host physiology
  - LS4_7Nutrition and exercise physiology
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  - LS4_9Metabolism and metabolic disorders, including diabetes and obesity
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  - LS3_8Embryogenesis, pattern formation, morphogenesis
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  - LS3_13Stem cells
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  - LS3_17Theoretical modelling in cellular, developmental and regenerative biology
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  - LS3_1Cell cycle, cell division and growth
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SHSocial Sciences and Humanities
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